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ASTM-E1759:1995 Edition

$35.75

E1759-95 Standard Test Method for Isoaspartic Acid in Proteins Method for the Determination of Asparagine Deamidation Products

Published By Publication Date Number of Pages
ASTM 1995 4
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ASTM E1759-95

Historical Standard: Standard Test Method for Isoaspartic Acid in Proteins Method for the Determination of Asparagine Deamidation Products

ASTM E1759

Scope

1.1 This test method covers the determination of isoaspartic acid residues in a protein or peptide sample. This test method is applicable for the determination of isoaspartic acid residues in a sample in the range of 2.5-50 [mu]mol/L. Higher concentrations can be determined following dilution. The reported lower range is based on single-operator precision.

1.2 The values stated in SI units are to be regarded as the standard.

1.3 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this standard to establish appropriate safety and health practices and determine the applicability of regulatory limitations prior to use.

Keywords

Asparagine deamidation products; Bioactive peptide protection; Biological protein activity; C-terminal amide; Deamidation; Isoaspartic acid residue; Microheterogeneity; Pharmaceutical proteins; Polypeptide chain; Protein damage; Residue; asparagine deamidation products-isoaspartic acid residue (in range; 2.5-50 micromoles/L) in proteins, test,;Order Form

ICS Code

ICS Number Code n/a

DOI: 10.1520/E1759-95

ASTM-E1759
$35.75