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BSI 20/30404078 DC 2020

BSI 20/30404078 DC 2020

$13.70

BS EN 16274. Method for Analysis of Allergens. Quantification of an extended list of 57 suspected allergens in ready to inject fragrance materials by gas chromatography mass spectrometry

Published By Publication Date Number of Pages
BSI 2020 71
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The present method permits the identification and quantification of the volatile compounds suspected as allergens, which are present in the fragrance compounds and raw materials used in cosmetic products. The analysis is performed by gas chromatography and mass spectrometry (GC-MS) on matrix samples which are “ready to be injected” and which are compatible with gas chromatography.

The analytes covered by this procedure are based on the contents of Tables 13.1 and 13.2 in the SCCS 1459/11 opinion document (1) and as listed in the legislation proposed by the European Commission. The rationale behind the final choice of procedure analytes is given in the table found in Annex J.

The method was validated at IFRA and CEN level with two solvents, namely methyl pivalate and tert-methyl butyl ether.

Many of the Allergens in the SCCS ‘Opinion’ documentation submitted to the EU Commission consist of multiple isomers of the same molecules and/or complex mixtures.

In many cases, this complexity can be resolved by this Procedure but that leaves a number of target analytes where this isn’t the case.

In addition, the SCCS Opinion also documents a number of CAS Numbers related to the same parent molecule. These are related to the optically active forms of the similar parent structure. For this procedure, the optically active forms are not considered as these require special (and in some cases, very different) GC phases to achieve the required separation.

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BSI 20/30404078 DC 2020
$13.70