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BSI PD ISO/TR 23463:2022

$167.15

Nanotechnologies. Characterization of carbon nanotube and carbon nanofiber aerosols in relation to inhalation toxicity tests

Published By Publication Date Number of Pages
BSI 2022 42
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PDF Catalog

PDF Pages PDF Title
2 National foreword
6 Foreword
7 Introduction
9 1 Scope
2 Normative references
3 Terms and definitions
15 4 Abbreviated terms
16 5 Considerations in CNT and CNF inhalation studies
5.1 General
5.2 Workplace exposure scenario
17 5.3 Existing inhalation toxicity testing guidelines
6 Physicochemical parameters related to the toxicity of CNTs and CNFs
6.1 General
6.2 Aerodynamic properties of aerosols for deposition of fibres
18 6.3 Size and shape (including length, width, aspect ratio, state of aggregation/agglomeration, and rigidity)
19 6.4 Specific surface area
6.5 Crystalline structure and defects
6.6 Surface chemistry, functionalization, surface charge, impurities, and radical generation/scavenging potential
20 6.7 Biodurability
7 Issues for the characterization of CNT and CNF aerosols
7.1 General
21 7.2 Characterization of physicochemical properties of CNT and CNF prior to aerosol generation
7.2.1 General
7.2.2 Size and size distribution
22 7.2.3 Shape (rigidity and agglomeration/aggregation)
7.2.4 Surface area
7.2.5 Crystalline structures
7.2.6 Surface chemistry, functionalization, surface charge, and radical generation/scavenging potential
7.2.7 Composition, purity, and impurities
23 7.2.8 Biodurability (in vivo and in vitro tests)
7.3 CNT and CNF aerosol characterization (sampling and measurement)
7.3.1 General
24 7.3.2 Size and size distribution of CNT and CNF aerosols
26 7.3.3 The shape of CNT and CNF aerosols
7.3.4 Crystalline structure and defects
27 7.3.5 Surface chemistry
7.3.6 Composition analysis
7.3.7 Fibre density
7.3.8 Concentration
28 7.4 Direct and indirect measurement
7.4.1 Direct measurement
29 7.4.2 Indirect measurement
30 Annex A (informative) Physicochemical properties of CNT associated with biological activity
31 Annex B (informative) CNT and CNF aerosol monitoring instruments
34 Bibliography
BSI PD ISO/TR 23463:2022
$167.15